That last paragraph is spot on for me. I occasionally beat a run on the lowest difficulty, but I’m so committed to my platonic ideal of the over-the-top silly deck that goes all in on a single mechanic that I always play as if that’s going to work. It usually fails, sometimes on a boss that is purpose-built to punish my deck, but that’s not the point. There are absolutely optimal ways to play, items to pick, cards to prioritise, and there is some satisfaction in piecing together a winning run. But I prefer the gamblers rush from getting just the right relic to turn my gimmicky single-mechanic deck into a hurtling juggernaut of bullshit.